| ORIGINAL ARTICLE |
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| Year : 2021 | Volume
: 12
| Issue : 4 | Page : 408-413 |
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Evaluating the effect of pretreatment with matrix metalloproteinase inhibitors on the shear bond strength of composite resin to primary teeth dentin: A 6-month in vitro study
Zahra Parsaie1, Maryam Firouzmandi2, Najmeh Mohammadi1
1 Department of Pediatric Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
2 Department of Operative Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
Correspondence Address:
Najmeh Mohammadi
Department of Pediatric Dentistry, School of Dentistry, Qasrodasht St., Shiraz, 71956-15878
Iran
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ccd.ccd_662_20
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Objective: The purpose of this study was to evaluate the effect of pretreatment with of matrix metalloproteinase inhibitors on the shear bond strength (SBS) of Adper Single Bond 2 total etch adhesive to the primary teeth dentin following 6 months of storage in artificial saliva. Materials and Methods: One hundred and twenty primary anterior teeth extracted for orthodontic reasons were selected. After etching, dentin blocks from each tooth were pretreated for 60 s with: (i) phosphate-buffered saline (0.01 M, pH 7.2) as the control group, (ii) 17% ethylenediaminetetraacetic acid (EDTA), (iii) 2% doxycycline (DO) solution, and (iv) 2% chlorhexidine (CHX) solution, with subsequent application of an etch-and-rinse adhesive system (Adper Single Bond 2). The composite was placed in clear Teflon cylinders. The SBS values were determined immediately and following 6 months of aging with a universal testing machine. Failure mode was evaluated using the stereomicroscope and scanning electron microscope. Data were analyzed by the SPSS software using the one-way analysis of variance and post hoc tests (P = 0.05). Results: At baseline, no significant difference was observed between control, EDTA, CHX, and DO groups (P = 0.554). Following 6 months of aging, the SBS of the CHX group was significantly higher than the control group (P = 0.013). However, the SBS of the control, EDTA, and DO groups was not statistically different (P < 0.05). Conclusions: Following 6 months of aging, among different groups of the study, only CHX significantly preserved the SBS of composite resin to primary teeth dentin using Adper Single Bond 2 adhesive.
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